The Brothers Brick is organizing efforts to help those affected by the recent earthquake and tsunami in Japan. They have banners on the site where you can donate to the Red Cross, and they are currently organizing a series of auctions via Creations for Charity. If you recall Creations for Charity usually has a big event around the holiday season where people can donate items to be sold and the proceeds were used to support Toys for Tots. This time around the items are being auctioned via eBay, but the mechanism is generally the same.
Over the holidays there was a strong show of support from minifig customizers for Creations for Charity. If you have the time, please help those affected in Japan.